import requestsimport urllib3urllib3.disable_warnings()def fetch_uniprot_data(uniprot_id): url =f"https://rest.uniprot.org/uniprotkb/{uniprot_id}.json" response = requests.get(url, verify=False) # Disable SSL verification response.raise_for_status() # Raise an error for bad status codesreturn response.json()def display_uniprot_data(data): primary_accession = data.get('primaryAccession', 'N/A') protein_name = data.get('proteinDescription', {}).get('recommendedName', {}).get('fullName', {}).get('value', 'N/A') gene_name = data.get('gene', [{'geneName': {'value': 'N/A'}}])[0]['geneName']['value'] organism = data.get('organism', {}).get('scientificName', 'N/A') function_comment =next((comment for comment in data.get('comments', []) if comment['commentType'] =="FUNCTION"), None) function = function_comment['texts'][0]['value'] if function_comment else'N/A'# Printing the dataprint(f"UniProt ID: {primary_accession}")print(f"Protein Name: {protein_name}")print(f"Organism: {organism}")print(f"Function: {function}")# Replace this with the UniProt ID you want to fetchuniprot_id ="O60235"data = fetch_uniprot_data(uniprot_id)display_uniprot_data(data)
UniProt ID: O60235
Protein Name: Transmembrane protease serine 11D
Organism: Homo sapiens
Function: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Preferentially cleaves the C-terminal side of arginine residues at the P1 position of certain peptides, cleaving Boc-Phe-Ser-Arg-4-methylcoumaryl-7-amide most efficiently and having an optimum pH of 8.6 with this substrate
More information:
AlphaFold model
WebGL does not seem to be available.
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The computed point cloud for pLDDT > 0.6. Each atom is sampled on average by 10 points.
To see the predicted binding interfaces, you can choose color theme “uncertainty”.
Go to the “Controls Panel”
Below “Components”, to the right, click on “…”
“Set Coloring” by “Atom Property”, and “Uncertainty/Disorder”
WebGL does not seem to be available.
This can be caused by an outdated browser, graphics card driver issue, or bad weather. Sometimes, just restarting the browser helps. Also, make sure hardware acceleration is enabled in your browser.
This can be caused by an outdated browser, graphics card driver issue, or bad weather. Sometimes, just restarting the browser helps. Also, make sure hardware acceleration is enabled in your browser.