import requestsimport urllib3urllib3.disable_warnings()def fetch_uniprot_data(uniprot_id): url =f"https://rest.uniprot.org/uniprotkb/{uniprot_id}.json" response = requests.get(url, verify=False) # Disable SSL verification response.raise_for_status() # Raise an error for bad status codesreturn response.json()def display_uniprot_data(data): primary_accession = data.get('primaryAccession', 'N/A') protein_name = data.get('proteinDescription', {}).get('recommendedName', {}).get('fullName', {}).get('value', 'N/A') gene_name = data.get('gene', [{'geneName': {'value': 'N/A'}}])[0]['geneName']['value'] organism = data.get('organism', {}).get('scientificName', 'N/A') function_comment =next((comment for comment in data.get('comments', []) if comment['commentType'] =="FUNCTION"), None) function = function_comment['texts'][0]['value'] if function_comment else'N/A'# Printing the dataprint(f"UniProt ID: {primary_accession}")print(f"Protein Name: {protein_name}")print(f"Organism: {organism}")print(f"Function: {function}")# Replace this with the UniProt ID you want to fetchuniprot_id ="Q9Y691"data = fetch_uniprot_data(uniprot_id)display_uniprot_data(data)
UniProt ID: Q9Y691
Protein Name: Calcium-activated potassium channel subunit beta-2
Organism: Homo sapiens
Function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons
More information:
AlphaFold model
Surface representation - binding sites
The computed point cloud for pLDDT > 0.6. Each atom is sampled on average by 10 points.
To see the predicted binding interfaces, you can choose color theme “uncertainty”.
Go to the “Controls Panel”
Below “Components”, to the right, click on “…”
“Set Coloring” by “Atom Property”, and “Uncertainty/Disorder”